It is a randomized controlled study, but it has some weaknesses such as the subjective report of side effects by the patients no clinical examination. The overall degree of patient satisfaction has not been evaluated. We did not demonstrate any difference regarding perineal irritation with any of the forms or routes assessed, despite a higher rate of vaginal discharge in the vaginal capsules group. More constipation and flatulence were associated with the rectal route.
We observed similar outcomes regarding pregnancy and implantation rates, even if the study was not powered enough to detect a significant difference in such parameters. Rectal administration of progesterone is as effective and safe as the vaginal route.
Paper subject to independent expert single-blind peer review. All editorial decisions made by independent academic editor. Upon submission manuscript was subject to anti-plagiarism scanning. Prior to publication all authors have given signed confirmation of agreement to article publication and compliance with all applicable ethical and legal requirements, including the accuracy of author and contributor information, disclosure of competing interests and funding sources, compliance with ethical requirements relating to human and animal study participants, and compliance with any copyright requirements of third parties.
Author Contributions. Conceived and designed the experiments: MK. Randomized the patients: KKB. Analyzed the data: MK, SS. Made critical revisions and approved final version: FZ, AZ. All authors reviewed and approved of the final manuscript. National Center for Biotechnology Information , U. Clin Med Insights Womens Health. Published online Jan 5. Find articles by Mohamed Khrouf.
Find articles by Soufiene Slimani. Find articles by Myriam Razgallah Khrouf. Find articles by Marouen Braham. Find articles by Maha Bouyahia. Find articles by Khadija Kacem Berjeb. Find articles by Hanene Elloumi Chaabane. Find articles by Ghaya Merdassi. Find articles by Aida Zahaf Kaffel. Find articles by Amel Zhioua. Find articles by Fethi Zhioua. Author information Article notes Copyright and License information Disclaimer. This article has been cited by other articles in PMC. RESULTS Fifty eight patients were assigned to the rectal pessaries group, 68 patients to the vaginal pessaries group, and 60 patients to the vaginal capsules group.
Keywords: progesterone, luteal phase support, rectal route, IVF. Dated August Ltd, The electronic Medicines Compendium. Dated October Dated February My girlfriend took 6 at home pregnancy tests - 4 were positive. The nurse couldn't give us an exact diagnosis - only her own opinion on whether or not my girlfriend Disclaimer: This article is for information only and should not be used for the diagnosis or treatment of medical conditions.
Egton Medical Information Systems Limited has used all reasonable care in compiling the information but make no warranty as to its accuracy. Consult a doctor or other health care professional for diagnosis and treatment of medical conditions. For details see our conditions. Progesterone is a natural female sex hormone. In this article About progesterone Before taking progesterone How to take progesterone Getting the most from your treatment Can progesterone cause problems?
How to store progesterone Important information about all medicines. I have used both. I get on much better with cyclogest in the back way! Utrogesten is vaginal and I think it irritated my cervix and contributed to early bleeding x. Thanks so much - I'm gping to finish off my Utrogestan, it will do me through the 2ww, before hopefully buying Cyclogest. Thanks for all the information, it has really helped and put my mind at ease.
Good luck with your cycle and 2WW! About Log in Join. Join Write. Home About Posts Members. I know I just need reassurance, so any success stories using only Utrogestan?
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First time using utrogestan for my 2nd FET on Wednesday! Due to start progesterone tonight. I've only used cyclogest before, but. Cyclogest everyone. Anyone used Utrogestan?
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